I'd talk about SOMA (meaning body in latin i think) and the role of the body in the novel. I did BNW in a course at uni which was about how the concept of the body changes in 20th C literature.... it's an interesting, if highly complex, angle....
I think BNW is all about sex drugs and rock n' roll, but as someone mentioned, as a form of control rather than rebellion.
Maybe you could look at the idea of the outsiders who aren't part of the priveledged society... and is it a dystopia or utopia? just because the book is set up for an immediate, knee-jerk reaction going totalitarianism and dystopia doesn't mean you have to think about it that way. Challenge the logic of the text,, it's fun
